Current Research Projects
1. De Novo Gastro Oesophageal Reflux Post Sleeve Gastrectomy
Acid reflux after sleeve gastric to me is a significant concern for many patients. There have been many multi centre studies that reveal a broad range of incidece of this problem. In this study we incorporated patients that followed a standard uniform procedure using a consistent bougie size, thereby reducing the inter surgeon variability of doing this procedure. Most of the data has been collected and we are in the process of analysis and writing our results.
2. The Change in Gut Microbiome post MGB/OAGB
The MGB/OAGB is a very powerful weight-loss operation, however it’s mechanism of action still deludes us. This procedure creates a significant impact in the gut microbiome and it potentially translates into patterns that correlate with post-surgical changes in the health status of the individuals. In this pilot study we collaborated with La Trobe University Microbiology Department to look further into the mysteries of the gut microbiome and how it changes after mini gastric bypass/OAGB surgery.
This study is almost complete and has been selected for presentation at the forthcoming conference of The American Society of Bariatric and Metabolic Surgeons in Las Vegas (US)
3. Alterations in Biliary Microbiome that lead to Gall stone formation
Gallstones are a very common biliary pathology requiring surgical intervention. The causes of gallstone formation delude us and there are various theories around the same. In this study, which was jointly done with University of Sydney, Professor Louis Vitatta, who generously sponsored the 16 S ribosomal RNA analysis of bile from patients undergoing gallbladder removal for goldstones. This study has finished recruiting and we hope to present the results soon.